Carboxylic Acid Derivatives

Carboxylic Acid Derivatives are cousins of carboxylic acid. Reactions and mechanism are resemble to the previous chapter with similar initiation of the reaction related to carbonyl group. (C=O)

An easy and fast way to study carboxylic acid derivatives in 10 minutes before the exam is to know carboxylic acid derivatives can be converted to carboxylic acids by a simple acidic or basic hydrolysis.

carboxylic acid derivative reaction1

The answer is

     ester

Mechanism - Must know !! It will assist all other reactions and to predict the products without too much memorization. How to see the products in 2 seconds.

carboxylic acid derivative reaction mechanism

 

What are the reactions to know? Acidic hydrolysis and basic hydrolysis. The core of these two mechanism is how you initiate the reaction. If you have the first part right, you have most of partial credits on the seconds parts of answers.

Basic Compounds are list below with the reactions that in acid, water and base.

How to use this chart... Example: Acid chloride in the left column reacts with Acid (on the top) -- to give a product of carboxylic acid.

 

Acid

 

Water

 

Base

Acid chloride

 

+

HCl

 

+

HCl

 

Acid Anhydrides

 

+

 

2 of

 

Esters

 

+

Need to add HCl to the reaction

+

 

Carboxylic Acid

 

+

 

 

N/A

 

 

 

 

 

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